Project Name Human Distal Gut Biome project 
Domain (1) bacteria
Investigators (1)
Institution The State University of New York at Buffalo
Project Code CAM_PROJ_HumanDistalGut
Project Type metagenome
Publications (1)


The human intestinal microbiota is composed of 1013 to 1014 microorganisms whose collective genome ("microbiome") contains at least 100 times as many genes as our own genome. We analyzed ~78 million base pairs of unique DNA sequence and 2062 polymerase chain reaction.amplified 16S ribosomal DNA sequences obtained from the fecal DNAs of two healthy adults. Using metabolic function analyses of identified genes, we compared our human genome with the average content of previously sequenced microbial genomes. Our microbiome has significantly enriched metabolism of glycans, amino acids, and xenobiotics; methanogenesis; and 2-methyl-D-erythritol 4-phosphate pathway-mediated biosynthesis of vitamins and isoprenoids. Thus, humans are superorganisms whose metabolism represents an amalgamation of microbial and human attributes.


No assemblies.


Sample Name PI Desc
HUMANDISTALGUT_SMPL_BIFIDOBACTERIUMLONGUM NA Bifidobacterium Longum
HUMANDISTALGUT_SMPL_METHANOBREVIBACTERSMITHII NA Methanobrevibacter Smithii
HUMANDISTALGUT_SMPL_UNCULTUREDBACTERIA NA Uncultured Bacteria